| Characteristic | Detail |
|---|---|
| Generic Name | Nifedipine |
| Formulation | Tablets, Extended-release Tablets |
| Dosages | 5 mg, 10 mg, 20 mg |
| Storage Temperature | 15-25°C (59-77°F) |
| Prescribed For | Hypertension, Angina |
| Common Side Effects | Dizziness, Headache, Flushing |
| Visit Adalat | |
Chemical Structure
Nifedipine, marketed under the brand name Adalat, is a potent calcium channel blocker. The chemical formula is C17H18N2O6. Its molecular weight is approximately 346.3 g/mol. The structure comprises a dihydropyridine core with ester and nitro groups enhancing its activity.
Adalat’s structure enables interaction with the L-type calcium channels. It has a distinct hydrophobic aromatic ring. This facilitates membrane partitioning, allowing selective binding to vascular smooth muscle.
Mechanism of Action
Nifedipine acts by blocking calcium influx in smooth muscle cells. By inhibiting the transmembrane calcium current, it causes vasodilation. This decreases peripheral vascular resistance, reducing blood pressure.
In the cardiac tissue, Adalat’s action mitigates myocardial oxygen demand. The drug prolongs the refractory period of the AV node. This dual effect ameliorates angina symptoms by enhancing coronary blood flow.
Indications
Adalat is primarily indicated for managing hypertension. It is effective as a first-line agent for lowering blood pressure. Clinical trials support its use for stable and variant angina.
In cases of Raynaud’s phenomenon, Adalat 10 mg demonstrates therapeutic benefits. Its vasodilatory action alleviates symptoms of peripheral vascular disorders.
Adalat Storage
Proper storage conditions preserve Adalat’s efficacy. It should be kept at room temperature, away from excess heat. Moisture and direct sunlight can compromise the drug’s stability.
It is essential to store the medication in its original container. An airtight closure prevents exposure to atmospheric elements. The ideal storage range is between 15-25°C (59-77°F).
Side Effects
Adalat usage may result in several side effects. Commonly reported ones include dizziness and headaches. Flushing and peripheral edema are associated with its vasodilatory properties.
Less frequent but significant adverse effects encompass palpitations. Patients may experience fatigue or gastrointestinal discomfort. It’s crucial to monitor for allergic reactions or severe hypotension.
Adalat Over The Counter
Adalat is not available over the counter. It requires a physician’s prescription. The necessity arises from its potent pharmacological profile.
Self-medication can lead to adverse cardiovascular events. Supervision by a healthcare provider ensures correct dosing. Medical guidance tailors therapy to individual patient needs.
For further insights, visit this detailed resource on calcium channel blockers: NCBI Article.
Data source:
- https://www.911mg.org/addiction-treatment/revia.htm
- https://duthuyenhalonglanha.com/teo-thi-giac-kham-pha-nhung-cai-tien-trong-dieu-tri/
- https://al-raied.com/exploring-somatropin-rdna-and-tb-vaccine-a-healthcare-revolution/
- https://www.fairymeadowsibexlodge.com/vizimpro-efficacy-in-advanced-non-small-cell-lung-cancer/
- https://intensotandil.com/tourette-syndrome-a-focus-on-treatment/
- https://celebs9ja.com/stroke-assessing-treatment-approaches-in-adhd/
- https://mtnlimousine.com/tb-tuberculosis-a-new-angle-in-pain-management/
- http://libertycom.com/exploring-dificid-its-role-in-combating-avian-influenza/
- https://www.911mg.org/erectile-dysfunction/aurogra.htm
- https://baronesaveiculos.com/doenca-renal-cronica-e-suporte-metabolico/